ARG56144
anti-CD83 antibody [HB15e]
anti-CD83 antibody [HB15e] for CyTOF®-candidate,Flow cytometry,IHC-Frozen sections and Human,Primates
概述
| 产品描述 | Mouse Monoclonal antibody [HB15e] recognizes CD83 |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | CyTOF®-candidate, FACS, IHC-Fr |
| 特异性 | This antibody recognizes CD83, a 40-45 kDa type I glycoprotein expressed on mature dendritic cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | HB15e |
| 同位型 | IgG1 |
| 靶点名称 | CD83 |
| 抗原物种 | Human |
| 抗原 | Human CD83-transfected Cos cells. |
| 偶联标记 | Un-conjugated |
| 別名 | hCD83; CD83 antigen; CD antigen CD83; HB15; BL11; Cell surface protein HB15; B-cell activation protein |
应用说明
| 应用建议 |
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| 应用说明 | IHC-Fr: Acetone fixation * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | FACS: Peripheral blood-derived dendritic cells. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD83 |
| 全名 | CD83 molecule |
| 背景介绍 | The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| 生物功能 | May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation. [UniProt] |
| 产品亮点 | Related products: CD83 antibodies; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies Detecting exosomal HMGB1 for ICD research |
| 预测分子量 | 23 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56144 anti-CD83 antibody [HB15e] FACS image
Flow Cytometry: Separation of IFN alpha-stimulated human monocytes (red) from unstimulated peripheral blood mononuclear cells (black). Cells were stained with ARG56144 anti-CD83 antibody [HB15e] at 2 µg/ml dilution, followed by APC-conjugated Goat anti-Mouse antibody.
