ARG21979

anti-CD4 antibody [GK1.5]

anti-CD4 antibody [GK1.5] for Flow cytometry,IHC-Frozen sections,ICC/IF,Immunoprecipitation,Depletion,Blocking and Mouse

Overview

Product Description Rat Monoclonal antibody [GK1.5] recognizes CD4
Tested Reactivity Ms
Tested Application BL, Depletion, FACS, ICC/IF, IHC-Fr, IP
Specificity Mouse CD4
Host Rat
Clonality Monoclonal
Clone GK1.5
Isotype IgG2bκ
Target Name CD4
Antigen Species Mouse
Immunogen Mouse CTL clone V4
Conjugation Un-conjugated
Full Name CD4 antigen
Alternate Names CD4mut; CD antigen CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3

Application Instructions

Application Suggestion
Application Dilution
BLAssay-dependent
DepletionAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IPAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer BBS (pH 8.2)
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 12504 Mouse CD4

Swiss-port # P06332 Mouse T-cell surface glycoprotein CD4

Gene Symbol CD4
Gene Full Name CD4 antigen
Background This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
Function Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. [UniProt]
PTM Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.

Images (1) Click the Picture to Zoom In

  • ARG21979 anti-CD4 antibody [GK1.5] FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG21979 anti-CD4 antibody [GK1.5] followed by ARG21709 Mouse anti-Rat IgG2b antibody [2B10A8] (PE).