ARG63963
anti-CD230 / Prion protein antibody
anti-CD230 / Prion protein antibody for Western blot and Human
Developmental Biology antibody; Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes CD230 / Prion protein |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow, Pig |
| 应用 | WB |
| 特异性 | Reported variants represent identical protein (NP_000302.1; NP_898902.1; NP_001073590.1; NP_001073591.1; NP_001073592.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD230 / Prion protein |
| 抗原物种 | Human |
| 抗原 | C-SDYEDRYYREN |
| 偶联标记 | Un-conjugated |
| 別名 | GSS; PrPc; PrP33-35C; PrP27-30; Alternative prion protein; p27-30; CJD; ASCR; CD230; PrP; PRIP; KURU; AltPrP |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| 研究领域 | Developmental Biology antibody; Neuroscience antibody |
| 预测分子量 | 9 kDa |
| 翻译后修饰 | The glycosylation pattern (the amount of mono-, di- and non-glycosylated forms or glycoforms) seems to differ in normal and CJD prion. Isoform 2 is sumoylated with SUMO1. |
检测图片 (1) Click the Picture to Zoom In
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ARG63963 anti-CD230 / Prion protein antibody WB image
Western blot: Human Brain lysate (35 µg protein in RIPA buffer) stained with ARG63963 anti-CD230 / Prion protein antibody at 0.3 µg/ml dilution.
