ARG23482
anti-CD2 antibody [CC42] (FITC)
anti-CD2 antibody [CC42] (FITC) for Flow cytometry and Bovine,Goat
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [CC42] recognizes CD2 Mouse anti Bovine CD2, clone CC42, recognizes the bovine homologue of human CD2. Clone CC42 inhibits rosetting with SRBC and stains cells in primary and secondary lymphoid organs in patterns consistent with those seen by human CD2 monoclonal antibodies. |
|---|---|
| 反应物种 | Bov, Goat |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | CC42 |
| 同位型 | IgG1 |
| 靶点名称 | CD2 |
| 抗原物种 | Bovine |
| 偶联标记 | FITC |
| 別名 | T-cell surface antigen T11/Leu-5; LFA-3 receptor; T-cell surface antigen CD2; SRBC; Erythrocyte receptor; CD antigen CD2; T11; Rosette receptor; LFA-2 |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide and 1% BSA. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CD2 |
|---|---|
| 全名 | CD2 molecule |
| 背景介绍 | CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010] |
| 生物功能 | CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (7) Click the Picture to Zoom In
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Bovine peripheral blood lymphocytes stained with ARG23482 anti-CD2 antibody [CC42] (FITC).
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Figure A. ARG23482 anti-CD2 antibody [CC42] (FITC) and RPE conjugated Mouse IgG2a isotype control. Figure B. ARG23482 anti-CD2 antibody [CC42] (FITC) and RPE conjugated Mouse anti Bovine CD4. All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Figure A. RPE conjugated Mouse anti Bovine CD4 and FITC conjugated Mouse IgG1 isotype control. Figure B. RPE conjugated Mouse anti Bovine CD4 and ARG23482 anti-CD2 antibody [CC42] (FITC). All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Figure A. ARG23482 anti-CD2 antibody [CC42] (FITC) and RPE conjugated Mouse IgG2a isotype control. Figure B. ARG23482 anti-CD2 antibody [CC42] (FITC) and RPE conjugated Mouse anti Bovine CD8. All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Figure A. RPE conjugated Mouse anti Bovine CD8 and FITC conjugated Mouse IgG1 isotype control. Figure B. RPE conjugated Mouse anti Bovine CD4 and ARG23482 anti-CD2 antibody [CC42] (FITC). All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Figure A. RPE conjugated Mouse anti Bovine CD335 and FITC conjugated Mouse IgG1 isotype control. Figure B. RPE conjugated Mouse anti Bovine CD335 and ARG23482 anti-CD2 antibody [CC42] (FITC). All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23482 anti-CD2 antibody [CC42] (FITC) FACS image
Flow Cytometry: Figure A. ARG23482 anti-CD2 antibody [CC42] (FITC) and RPE conjugated Mouse IgG1 isotype control. Figure B. ARG23482 anti-CD2 antibody [CC42] (FITC) and RPE conjugated Mouse anti Bovine CD335. All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
