ARG56924

anti-BMP7 antibody [4E7]

anti-BMP7 antibody [4E7] for ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Mouse Monoclonal antibody [4E7] recognizes BMP7
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Mouse
克隆 Monoclonal
克隆号 4E7
同位型 IgG1, kappa
靶点名称 BMP7
抗原物种 Human
抗原 Recombinant fragment around aa. 293-431 of Human BMP7.
偶联标记 Un-conjugated
別名 BMP-7; OP-1; Osteogenic protein 1; Eptotermin alfa; Bone morphogenetic protein 7

应用说明

应用建议
应用 推荐稀释比
ICC/IFAssay-dependent
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 10% Glycerol
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 12162 Mouse BMP7

GeneID: 655 Human BMP7

Swiss-port # P18075 Human Bone morphogenetic protein 7

Swiss-port # P23359 Mouse Bone morphogenetic protein 7

基因名称 BMP7
全名 bone morphogenetic protein 7
背景介绍 The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
生物功能 Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. [UniProt]
预测分子量 49 kDa
翻译后修饰 Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms.

检测图片 (3) Click the Picture to Zoom In

  • ARG56924 anti-BMP7 antibody [4E7] ICC/IF image

    Immunoflorescense: HeLa cell line stained with ARG56924 anti-BMP7 antibody [4E7] at 1:100 (Green).

    DAPI (Blue) for nucleus staining.

  • ARG56924 anti-BMP7 antibody [4E7] WB image

    Western blot: 40 µg of Mouse brain tissue lysates stained with ARG56924 anti-BMP7 antibody [4E7] at 1:1000.

  • ARG56924 anti-BMP7 antibody [4E7] WB image

    Western blot: Mouse kidney (MK) and Rat heart (RH) stained with ARG56924 anti-BMP7 antibody [4E7] at 1:1000.