ARG43625
anti-ADAM28 antibody
anti-ADAM28 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ADAM28 |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ADAM28 |
| 抗原物种 | Rat |
| 抗原 | Recombinant fragment corresponding to a.a. K26-K195 of Rat ADAM28. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Disintegrin and metalloproteinase domain-containing protein 28 |
| 別名 | Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; eMDC II; EC 3.4.24.-; MDC-L; MDCL; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; Disintegrin and metalloproteinase domain-containing protein 28; eMDCII; ADAM 28 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 87, 61 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | Adam28 |
|---|---|
| 全名 | ADAM metallopeptidase domain 28 |
| 背景介绍 | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| 生物功能 | May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. [UniProt] |
| 细胞定位 | Cell membrane; Membrane; Secreted |
| 预测分子量 | 87 kDa |
| 翻译后修饰 | Pro-domain removal and maturation may be, at least in part, autocatalytic. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG43625 anti-ADAM28 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded mouse lung tissue blocked with 10% goat serum, then stained with ARG43625 anti-ADAM28 antibody at 1:500 dilution overnight at 4°C. Antigen Retrieval: Heat mediated was performed using EDTA buffer (pH 8.0).
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ARG43625 anti-ADAM28 antibody WB image
Western blot: Rat brain tissue lysates stained withARG43625 anti-ADAM28 antibody at 1:1000 dilution.
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ARG43625 anti-ADAM28 antibody IHC-P image FACS image
Flow Cytometry: HEPA1-6 cells were stained with ARG43625 anti-ADAM28 antibody at 1:500 dilution, 1 μg / 10^6 .
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ARG43625 anti-ADAM28 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded rat gaster tissuee blocked with 10% goat serum, then stained with ARG43625 anti-ADAM28 antibody at 1:500 dilution overnight at 4°C. Antigen Retrieval: Heat mediated was performed using EDTA buffer (pH 8.0).
