ARG80186
Human Neuroserpin ELISA Kit
Human Neuroserpin ELISA 试剂盒 for ELISA and Human
Neuroscience kit
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG80186-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG80186-002 | Standard (Lyophilized) | 3 X 4 ng/vial | 4°C |
| ARG80186-003 | Standard diluent buffer | 20 ml | 4°C |
| ARG80186-004 | Antibody conjugate concentrate | 400 µl | 4°C |
| ARG80186-005 | Antibody diluent buffer | 16 ml | 4°C |
| ARG80186-006 | HRP-Streptavidin concentrate | 400 µl | 4°C (Protect from light) |
| ARG80186-007 | HRP-Streptavidin diluent buffer | 16 ml | 4°C |
| ARG80186-008 | 20X Wash buffer | 50 ml | 4°C |
| ARG80186-009 | TMB substrate | 12ml | 4°C (Protect from light) |
| ARG80186-010 | STOP solution | 12ml | 4°C |
| ARG80186-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG80186 Human Neuroserpin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Neuroserpin in Serum, Plasma, Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | No significant cross-reactivity or interference with Human IL-2,3,4,5,6,7,9,10,12, IFN- gamma, TNF- alpha；mouse neuroserpin |
| 靶点名称 | Neuroserpin |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 30 pg/ml |
| 样品类型 | Serum, Plasma, Cell culture supernatants |
| 标准范围 | 62.5 - 4000 pg/ml |
| 样本量 | 100 µl |
| 精确 | CV: less than10% |
| 別名 | Peptidase inhibitor 12; neuroserpin; Neuroserpin; Serpin I1; PI12; PI-12 |
应用说明
| 检测时间 | 4 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SERPINI1 |
| 全名 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| 背景介绍 | Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala. The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB). Recombinant human neuroserpin is a 44.6 kDa non-glycosylated protein containing 394 amino-acid residues. |
| 产品亮点 | Related products: Neuroserpin antibodies; Neuroserpin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Neuroscience kit |
检测图片 (1) Click the Picture to Zoom In
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ARG80186 Human Neuroserpin ELISA Kit standard curve image
ARG80186 Human Neuroserpin ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
|---|---|
| ARG80186 Human Neuroserpin ELISA Kit User's manual |
 Download
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