ARG70462
Human Galectin 8 recombinant protein (Active) (His-tagged, N-ter)
Human Galectin 8 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
概述
产品描述 | E. coli expressed, His-tagged (N-ter) Active Human Galectin 8 recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | Galectin 8 |
物种 | Human |
A.A. 序列 | Met2 - Trp317 |
表达系统 | E. coli |
Protein Full name | Galectin-8 |
生物活性 | Active |
活性说明 | Determinedd by its ability to agglutinate human red blood cells. The ED50 for this effect is < 8 μg/mL. |
別名 | LGALS8; Galectin 8; PCTA-1; Lectin, Galactoside-Binding, Soluble, 8; Prostate Carcinoma Tumor Antigen 1 Po66 Carbohydrate-Binding Protein; Galectin-8; Po66-CBP; Gal-8 |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | > 98% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.4) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | LGALS8 |
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全名 | Galectin 8 |
背景介绍 | This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. |
生物功能 | Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. |
细胞定位 | Cytoplasm, Cytoplasmic vesicle |
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