ARG70037

Human GM-CSF recombinant protein (Active) (His-tagged, N-ter)

Human GM-CSF recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE

概述

产品描述 E. coli expressed, His-tagged (N-ter) Active Human GM-CSF recombinant protein
应用 SDS-PAGE
靶点名称 GM-CSF
物种 Human
A.A. 序列 APARS PSPST QPWEH VNAIQ EARRL LNLSR DTAAE MNETV EVISE MFDLQ EPTCL QTRLE LYKQG LRGSL TKLKG PLTMM ASHYK QHCPP TPETS CATQI ITFES FKENL KDFLL VIPFD CWEPV QE with polyhistidine tag at the N-terminus.
表达系统 E. coli
活动 Active
活动说明 Determined by its ability to induce TF-1 cells proliferation. The ED50 for this effect is < 0.5 ng/ml.
別名 GM-CSF; Granulocyte-macrophage colony-stimulating factor; CSF; GMCSF; Molgramostin; Colony-stimulating factor; Sargramostim

属性

形式 Powder
纯化 Ni-NTA chromatography.
纯化说明 Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度 > 98% (by SDS-PAGE)
缓冲液 PBS (pH 8.0)
重建 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 µg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
存放说明 Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 CSF2
全名 colony stimulating factor 2 (granulocyte-macrophage)
背景介绍 The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
生物功能 Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. [UniProt]
细胞定位 Secreted. [UniProt]
产品亮点 Related products:
GM-CSF antibodies; GM-CSF ELISA Kits; GM-CSF Duos / Panels; GM-CSF recombinant proteins;
Related news:
HMGB1 in inflammation
Inflammatory Cytokines

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  • ARG70037 Human GM-CSF recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image

    SDS-PAGE analysis of ARG70037 Human GM-CSF recombinant protein (Active) (His-tagged, N-ter).