ARG70476
Human CCL3 / MIP1 alpha recombinant protein (Active) (His-Tagged, N-ter)
Human CCL3 / MIP1 alpha recombinant protein (Active) (His-Tagged, N-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-Tagged (N-ter)Active Human CCL3 / MIP1 alpha recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CCL3 / MIP1 alpha |
| 物种 | Human |
| A.A. 序列 | Ala27 - Ala92 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Measure by its ability to chemoattract human PBMC using a concentration range of 5 -50 ng/mL. |
| 別名 | CCL3; C-C Motif Chemokine Ligand 3; G0S19-1; MIP-1-Alpha; LD78ALPHA; SCYA3; Small Inducible Cytokine A3 (Homologous To Mouse Mip-1a); Macrophage Inflammatory Protein 1-Alpha; Tonsillar Lymphocyte LD78 Alpha Protein; G0/G1 Switch Regulatory Protein 19-1; C-C Motif Chemokine; PAT 464.1; SIS-Beta; MIP1A; LD78; SCI; Macrophage Inflammatory Protein 1 Alpha; Chemokine (C-C Motif) Ligand; Small-Inducible Cytokine A3; MIP-1-ALPHA |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not < 200 µg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CCL3 |
|---|---|
| 全名 | C-C Motif Chemokine Ligand 3 |
| 背景介绍 | This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1 |
| 生物功能 | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond |
检测图片 (1) Click the Picture to Zoom In
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ARG70476 Human CCL3 / MIP1 alpha recombinant protein (Active) (His-Tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70476 Human CCL3 / MIP1 alpha recombinant protein (Active) (His-Tagged, N-ter)
