Inflammasome & Pyroptosis Antibody Panels are released

Pyroptosis is an inflammatory programmed cell death. It is induced by inflammasome which is a multiprotein complex assembled in response to pathogens. The inflammasome activates caspase-1 which then not only mediates the proteolytic maturation of inflammatory cytokines IL-1 beta and IL-18 but also induces pyroptosis.

arigo is proud to introduce the newly released antibody panels for studying the NLRP3 inflammasome, NLRC4 inflammasome, and pyriotosis.

▶ Pyroptosis Antibody Panel (ARG30330)

* Includes the antibodies against the key proteins Caspase-1, GSDMD, and IL-1 beta.
* Excellent for detecting both pro- and cleaved forms of the key proteins.
* Includes the most suitable loading control.
* Works on human and mouse samples.

Component	Reactivity	Application	Pkg
Caspase-1 antibody	Hu, Ms	ICC/IF, IHC-P, IP, WB	20 ul
GSDMD antibody	Hu, Ms, Rat	ICC/IF, WB	20 ul
IL-1 beta antibody [SQab1748]	Hu, Ms	ELISA, FACS, ICC/IF, IHC-P, WB	20 ug
beta-Tubulin antibody [BT7R]	Hu, Ms, Rat, Ch, Mk, Rb	ELISA, ICC/IF, WB	20 ug

▶ NLRP3 Inflammasome Antibody Panel (ARG30331)

* Includes NLRP3 inflammasome components NLRP3, ASC and Caspase-1 antibodies.
* Includes the most suitable loading control.
* Works on human and mouse samples.

Component	Reactivity	Application	Pkg
NLRP3 antibody	Hu, Ms, Rat	ICC/IF, IHC-P, WB	20 ul
ASC antibody	Hu, Ms	WB	20 ul
Caspase-1 antibody	Hu, Ms	ICC/IF, IHC-P, IP, WB	20 ul
GAPDH antibody	Hu, Ms, Rat, Mk, Bb, Cat, Ck, Dog, Fsh, Hm, Mk, Pig, Rb, Xl	ELISA, ICC/IF, IHC-Fr, WB	20 ug

▶ NLRC4 Inflammasome Antibody Panel (ARG30332)

* Includes NLRC4 inflammasome components NLRC4, ASC and Caspase-1 antibodies.
* Includes the most suitable loading control.
* Works on human and mouse samples.

Component	Reactivity	Application	Pkg
NLRC4 antibody	Hu, Ms	ICC/IF, IHC-P, WB	20 ul
ASC antibody	Hu, Ms	WB	20 ul
Caspase-1 antibody	Hu, Ms	ICC/IF, IHC-P, IP, WB	20 ul
GAPDH antibody	Hu, Ms, Rat, Mk, Bb, Cat, Ck, Dog, Fsh, Hm, Mk, Pig, Rb, Xl	ELISA, ICC/IF, IHC-Fr, WB	20 ug

▶ GSDME-mediated Pyroptosis Antibody Panel (ARG30343)

* Includes Caspase-3 antibody for detecting both pro- and cleaved forms.
* Includes GSDME antibody for detecting both pro- and cleaved forms.
* Includes HMGB1 antibody for detecting lytic cell death.
* Works on human, mouse and rat samples.

Component	Reactivity	Application	Pkg
Caspase-3 antibody	Hu, Ms, Rat	ICC/IF, IHC, IP, WB	20 ul
GSDME antibody	Hu	IP, WB	20 ul
HMGB1 antibody [SQab1711]	Hu, Ms, Rat	ELISA, FACS, ICC/IF, IHC-P, WB	20 ul