ARG83792
arigoQIK® Mouse CD68 ELISA Development Kit
arigoQIK® Mouse CD68 ELISA Development 试剂盒 for ELISA and Mouse
概述
| 产品描述 | ARG83792 arigoQIK® Mouse CD68 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Mouse CD68 in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More aboutarigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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| 反应物种 | Ms |
| 应用 | ELISA |
| 靶点名称 | CD68 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 20 pg/mL |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 39.06-2500 pg/mL |
| 样本量 | 50 μL |
| 精确 | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| 別名 | Macrosialin; CD antigen CD68; LAMP4; Gp110; GP110; SCARD1 |
属性
| 存放说明 | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
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| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | Cd68 |
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| 全名 | CD68 antigen |
| 背景介绍 | CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. [UniProt] |
| 产品亮点 | Related news: arigoQIK, DIY your sandwich ELISA kits; |
| 翻译后修饰 | N- and O-glycosylated. |
| Title | Download Link |
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| ARG83792 arigoQIK® Mouse CD68 ELISA Development Kit User Manual |
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