ARG22357
anti-pan FGFA / FHFA antibody [S235-22]
anti-pan FGFA / FHFA antibody [S235-22] for ICC/IF,Western blot and Human,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [S235-22] recognizes pan FGFA / FHFA |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms |
| 应用 | ICC/IF, WB |
| 特异性 | Does not cross-react with FGF13B / FHF2B. Cross reacts with FGF12A / FHF1A and FGF14A / FHF4A. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | S235-22 |
| 同位型 | IgG2b |
| 靶点名称 | pan FGFA / FHFA |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 2-18 of Human FHF2A (AAAIASSLIRQKRQARE). 100% identical to Rat, 94% identical to Mouse. > 80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A. |
| 偶联标记 | Un-conjugated |
| 別名 | FHF-2; FHF2; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; FGF-13; FGF2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.1% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FGF13 |
| 全名 | fibroblast growth factor 13 |
| 背景介绍 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008] |
| 生物功能 | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. May regulate voltage-gated sodium channels transport and function. May also play a role in MAPK signaling. [UniProt] |
| 预测分子量 | 28 kDa |
| 翻译后修饰 | May be phosphorylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG22357 anti-pan FGFA / FHFA antibody [S235-22] ICC/IF image
Immunocytochemistry: Human Neuroblastoma cell line SK-N-BE. Fixation: 4% Formaldehyde for 15 min at RT. Cells were stained with ARG22357 anti-pan FGFA / FHFA antibody [S235-22] at 1:100 dilution (60 min, RT). Magnification: 60X. (A) DAPI (blue) nuclear stain, (B) Phalloidin Texas Red F-Actin stain, (C) ARG22357 anti-pan FGFA / FHFA antibody [S235-22] (green), and (D) Composite.
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ARG22357 anti-pan FGFA / FHFA antibody [S235-22] WB image
Western blot: 15 µg of Rat brain membrane stained with ARG22357 anti-pan FGFA / FHFA antibody [S235-22] at 1:200 dilution (16 hours, 4°C). Block: 2% BSA and 2% Skim Milk in 1X TBST. .
