ARG57483
anti-p70 S6 Kinase antibody
anti-p70 S6 Kinase antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes p70 S6 Kinase |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, IP, WB |
| 特异性 | This antibody detects endogenous levels of total p70 S6 Kinase. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | p70 S6 Kinase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human p70 S6 Kinase. |
| 偶联标记 | Un-conjugated |
| 別名 | S6K-beta2; p70 ribosomal S6 kinase beta; Ribosomal protein S6 kinase beta-2; S6 kinase-related kinase; S6K-beta-2; p70-beta; p70 S6K-beta; p70 S6 kinase beta; p70S6Kb; STK14B; p70 S6KB; p70-S6K 2; P70-beta-1; P70-beta-2; S6K2; SRK; P70S6K2; KLS; Serine/threonine-protein kinase 14B; S6K-beta; P70-beta; p70(S6K)-beta; 70 kDa ribosomal protein S6 kinase 2; EC 2.7.11.1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UBS0 Human Ribosomal protein S6 kinase beta-2 Swiss-port # Q9Z1M4 Mouse Ribosomal protein S6 kinase beta-2 |
|---|---|
| 基因名称 | RPS6KB2 |
| 全名 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| 背景介绍 | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015] |
| 生物功能 | Phosphorylates specifically ribosomal protein S6. [UniProt] |
| 预测分子量 | 53 kDa |
| 翻译后修饰 | Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention. |
检测图片 (1) Click the Picture to Zoom In
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ARG57483 anti-p70 S6 Kinase antibody WB image
Western blot: 293T cell lysate stained with ARG57483 anti-p70 S6 Kinase antibody.
