ARG64567
anti-mKIAA0319 antibody
anti-mKIAA0319 antibody for Western blot and Mouse
Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes mKIAA0319 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Rat |
| 应用 | WB |
| 特异性 | The variants XP_341528.2 and XP_001070349.1 represent identical protein. This antibody is expected to cross-react with mouse KIAA0319 isoform 1 (NP_001074520.1), isoform 2 (XP_994023.1) and isoform 4 (XP_913491.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | mKIAA0319 |
| 抗原物种 | Mouse |
| 抗原 | C-QGKIKQENKPTLH |
| 偶联标记 | Un-conjugated |
| 別名 | Dyslexia-associated protein KIAA0319; DYX2; DYLX2; NMIG |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | D130043K22Rik |
|---|---|
| 全名 | RIKEN cDNA D130043K22 gene |
| 背景介绍 | This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in a similar gene in human are associated with dyslexia. Alternatively spliced transcript variants have been identifed. [provided by RefSeq, May 2015] |
| 生物功能 | Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites (By similarity). [UniProt] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 118 kDa |
| 翻译后修饰 | N-glycosylated. O-glycosylated. Shedding of the extracellular domain and intramembrane cleavage produce several proteolytic products. The intramembrane cleavage releases a soluble cytoplasmic polypeptide that translocates to the nucleolus. |
检测图片 (1) Click the Picture to Zoom In
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ARG64567 anti-mKIAA0319 antibody WB image
Western Blot: Mouse Brain lysate (35 µg protein in RIPA buffer) stained with ARG64567 anti-mKIAA0319 antibody at 0.5 µg/ml dilution.
