ARG54077
anti-hnRNP U antibody
anti-hnRNP U antibody for Western blot and Human
Gene Regulation antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes HNRNPU |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | hnRNP U |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human hnRNP U protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | U21.1; p120; hnRNP U; Heterogeneous nuclear ribonucleoprotein U; SAFA; HNRPU; SAF-A; pp120; Scaffold attachment factor A |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.2% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q00839 Human Heterogeneous nuclear ribonucleoprotein U |
|---|---|
| 基因名称 | HNRNPU |
| 全名 | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| 背景介绍 | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. |
| 生物功能 | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity). [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Cell surface. |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 91 kDa |
| 翻译后修饰 | Extensively phosphorylated. Arg-739 is dimethylated, probably to asymmetric dimethylarginine. Citrullinated by PADI4. |
检测图片 (1) Click the Picture to Zoom In
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ARG54077 anti-hnRNP U antibody WB image
Western blot: Jurkat cell lysate stained with ARG54077 anti-hnRNP U antibody at 1:1000 dilution.
