ARG59704
anti-hemoglobin gamma antibody
anti-hemoglobin gamma antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes hemoglobin gamma |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody react to hemoglobin subunit gamma 1 and gamma 2. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | hemoglobin gamma |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human hemoglobin gamma. |
| 偶联标记 | Un-conjugated |
| 別名 | Hemoglobin gamma-1 chain; HBGR; HSGGL1; PRO2979; Hemoglobin subunit gamma-1; HBG-T2; Hemoglobin gamma-A chain; Gamma-1-globin; HBGA; Hb F Agamma |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 11 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HBG1 |
| 全名 | hemoglobin, gamma A |
| 背景介绍 | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008] |
| 生物功能 | Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. [UniProt] |
| 预测分子量 | 16 kDa |
| 翻译后修饰 | Acetylation of Gly-2 converts Hb F to the minor Hb F1. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59704 anti-hemoglobin gamma antibody WB image
Western blot: K562 cell lysate stained with ARG59704 anti-hemoglobin gamma antibody.
