ARG42557
anti-gamma Sarcoglycan antibody
anti-gamma Sarcoglycan antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes gamma Sarcoglycan |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | gamma Sarcoglycan |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human gamma Sarcoglycan. |
| 偶联标记 | Un-conjugated |
| 別名 | Breast cancer-specific gene 1 protein; Persyn; SR; Synoretin; BCSG1; Gamma-synuclein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human fetal brain | ||||||||
| 实际分子量 | ~ 16 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SNCG |
| 全名 | synuclein, gamma (breast cancer-specific protein 1) |
| 背景介绍 | This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010] |
| 生物功能 | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle. [UniProt] |
| 预测分子量 | 13 kDa |
| 翻译后修饰 | Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42557 anti-gamma Sarcoglycan antibody WB image
Western blot: Human fetal brain lysate stained with ARG42557 anti-gamma Sarcoglycan antibody.
