ARG59006
anti-eEF2k antibody
anti-eEF2k antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes eEF2k |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | eEF2k |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 337-371 of Human eEF2k. |
| 偶联标记 | Un-conjugated |
| 別名 | eEF-2K; CaMKIII; HSU93850 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa + TPA |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O00418 Human Eukaryotic elongation factor 2 kinase |
|---|---|
| 基因名称 | EEF2K |
| 全名 | eukaryotic elongation factor 2 kinase |
| 背景介绍 | This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008] |
| 生物功能 | Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. [UniProt] |
| 预测分子量 | 82 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59006 anti-eEF2k antibody WB image
Western blot: HeLa cells treated with TPA (200 nM) or untreated. The blots were stained with ARG59006 anti-eEF2k antibody.
