ARG56673
anti-beta NGF antibody
anti-beta NGF antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Neutralizing,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes beta NGF |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, IHC-P, Neut, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | beta NGF |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human beta NGF. (SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA) |
| 偶联标记 | Un-conjugated |
| 別名 | HSAN5; Beta-nerve growth factor; Beta-NGF; NGFB |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NGF |
| 全名 | nerve growth factor (beta polypeptide) |
| 背景介绍 | This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI. [UniProt] |
| 预测分子量 | 27 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG56673 anti-beta NGF antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded sections of Human pancreas adenocarcinoma. The recommended ARG56673 anti-beta NGF antibody concentration is 0.5 µg/ml with an overnight incubation at 4°C. An HRP-labeled polymer detection system was used with a DAB chromogen.
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ARG56673 anti-beta NGF antibody WB image
Western blot: 250 - 0.24 ng of Human beta NGF stained with ARG56673 anti-beta NGF antibody, under reducing conditions.
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ARG56673 anti-beta NGF antibody WB image
Western blot: 250 - 0.24 ng of Human beta NGF stained with ARG56673 anti-beta NGF antibody, under non-reducing conditions.
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ARG56673 anti-beta NGF antibody standard curve image
Sandwich ELISA: ARG56673 anti-beta NGF antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56783 anti-beta NGF antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
