ARG40584
anti-beta 2 Microglobulin antibody
anti-beta 2 Microglobulin antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes beta 2 Microglobulin |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | beta 2 Microglobulin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human beta 2 Microglobulin. |
| 偶联标记 | Un-conjugated |
| 別名 | Beta-2-microglobulin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | B2M |
| 全名 | beta-2-microglobulin |
| 背景介绍 | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014] |
| 生物功能 | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] |
| 细胞定位 | Secreted. Cell surface. Note=Detected in serum and urine (PubMed:1336137, PubMed:7554280). Note=(Microbial infection) In the presence of M.tuberculosis EsxA-EsxB complex decreased amounts of B2M are found on the cell surface (PubMed:25356553). [UniProt] |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Glycation of Ile-21 is observed in long-term hemodialysis patients. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG40584 anti-beta 2 Microglobulin antibody WB image
Western blot: U937 cell lysate stained with ARG40584 anti-beta 2 Microglobulin antibody.
