ARG67027

anti-alpha Fetoprotein antibody [SQab30312]

anti-alpha Fetoprotein antibody [SQab30312] for IHC-Formalin-fixed paraffin-embedded sections and Human

概述

产品描述 Recombinant rabbit Monoclonal antibody [SQab30312] recognizes alpha Fetoprotein
反应物种 Hu
应用 IHC-P
宿主 Rabbit
克隆 Monoclonal
克隆号 SQab30312
同位型 IgG
靶点名称 alpha Fetoprotein
抗原物种 Human
抗原 Synthetic peptide of Human alpha Fetoprotein.
偶联标记 Un-conjugated
Protein Full name Alpha-fetoprotein
別名 AFP, Alpha Fetoprotein, Alpha-Fetoprotein, HPAFP , FETA, Alpha-1-Fetoprotein, Alpha-Fetoglobulin, AFPD

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:100
应用说明 The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Hepatocellular carcinoma

属性

形式 Liquid
纯化 Purification with Protein A.
缓冲液 PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
抗菌剂 0.01% Sodium azide
稳定剂 40% Glycerol and 0.05%BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 174 Human AFP

Swiss-port # P02771 Human Alpha-fetoprotein

基因名称 AFP
全名 Alpha Fetoprotein
背景介绍 This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
生物功能 Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [Uniprot]
细胞定位 Secreted
预测分子量 69 kDa
翻译后修饰 Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. [Uniprot]

检测图片 (1) Click the Picture to Zoom In

  • ARG67027 anti-alpha Fetoprotein antibody [SQab30312] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded hepatocellular carcinoma stained with ARG67027 anti-alpha Fetoprotein antibody [SQab30312].