ARG44332
anti-alpha 2C Adrenergic Receptor / ADRA2C antibody
anti-alpha 2C Adrenergic Receptor / ADRA2C antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes alpha 2C Adrenergic Receptor / ADRA2C |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | alpha 2C Adrenergic Receptor / ADRA2C |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | DRA2C; Adrenoceptor Alpha 2C; ADRA2RL2; ADRARL2; ADRA2L2; Alpha-2 Adrenergic Receptor Subtype C4; Adrenergic, Alpha-2C-, Receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
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| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
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| 基因名称 | ADRA2C |
| 全名 | Adrenoceptor Alpha 2C |
| 背景介绍 | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. |
| 生物功能 | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. |
| 细胞定位 | Cell membrane, Membrane |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
