ARG45866
anti-Zebrafish vWF antibody
anti-Zebrafish vWF antibody for IHC-Formalin-fixed paraffin-embedded sections and Zebrafish
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes vWF |
|---|---|
| 反应物种 | Zfsh |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | vWF |
| 抗原物种 | Zebrafish |
| 偶联标记 | Un-conjugated |
| 別名 | VWD; von Willebrand factor; vWF; von Willebrand antigen II; F8VWF |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.02M PBS, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | VWF |
|---|---|
| 全名 | von Willebrand factor |
| 背景介绍 | The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008] |
| 生物功能 | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. [UniProt] |
| 细胞定位 | Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules. [UniProt] |
| 预测分子量 | 309 kDa |
| 翻译后修饰 | All cysteine residues are involved in intrachain or interchain disulfide bonds. N- and O-glycosylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45866 anti-Zebrafish vWF antibody IHC-P image
Immunohistochemistry: Zebrafish muscle stained with ARG45866 anti-Zebrafish vWF antibody at 2 μg/ml dilution.
