ARG45865
anti-Zebrafish USH2A antibody
anti-Zebrafish USH2A antibody for IHC-Frozen sections and Zebrafish
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes USH2A |
|---|---|
| 反应物种 | Zfsh |
| 应用 | IHC-Fr |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | USH2A |
| 抗原物种 | Zebrafish |
| 偶联标记 | Un-conjugated |
| 別名 | USH2A; Usherin; RP39; Usher Syndrome 2A (Autosomal Recessive, Mild); Usher Syndrome Type IIa Protein; Usher Syndrome Type-2A Protein; USH2; DJ1111A8.1; US2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.02% Sodium azide and 50% glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% glycerol |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | USH2A |
|---|---|
| 全名 | Usherin |
| 背景介绍 | This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| 生物功能 | Involved in hearing and vision as member of the USH2 complex. In the inner ear, required for the maintenance of the hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.. [UniProt] |
| 细胞定位 | Cell membrane; Cell projection; Membrane; Secreted. [UniProt] |
| 翻译后修饰 | Disulfide bond ; Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45865 anti-Zebrafish USH2A antibody IHC-Fr image
Immunohistochemistry: Frozen Zebrafish retina stained with ARG45865 anti-Zebrafish USH2A antibody at 1:200 dilution.
