ARG45861
anti-Zebrafish TFAP2A / AP2 alpha antibody
anti-Zebrafish TFAP2A / AP2 alpha antibody for IHC-Formalin-fixed paraffin-embedded sections and Zebrafish
概述
产品描述 | Rabbit Polyclonal antibody recognizes TFAP2A / AP2 alpha |
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反应物种 | Zfsh |
应用 | IHC-P |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | TFAP2A / AP2 alpha |
抗原物种 | Zebrafish |
偶联标记 | Un-conjugated |
別名 | TFAP2A; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); BOFS; TFAP2; Activating enhancer-binding protein 2-alpha; AP2-alpha; Transcription factor AP-2-alpha; AP-2; AP-2alpha; AP-2 transcription factor; Activator protein 2; AP2TF |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity chromatography purified |
缓冲液 | 0.02M PBS, 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% glycerol |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | TFAP2A |
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全名 | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
背景介绍 | The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] |
生物功能 | Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. [UniProt] |
预测分子量 | 48 kDa |
翻译后修饰 | Sumoylated on Lys-10; which inhibits transcriptional activity. [UniProt] |
检测图片 (1) Click the Picture to Zoom In