ARG45839
anti-Zebrafish KIAA1199 antibody
anti-Zebrafish KIAA1199 antibody for IHC-Formalin-fixed paraffin-embedded sections and Zebrafish
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KIAA1199 |
|---|---|
| 反应物种 | Zfsh |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KIAA1199 |
| 抗原物种 | Zebrafish |
| 偶联标记 | Un-conjugated |
| 別名 | CEMIP; Cell Migration Inducing Hyaluronidase 1; KIAA1199; HYBID; TMEM2L; CEMIP1; Hyaluronan-Binding Protein Involved In Hyaluronan Depolymerization; Cell Migration-Inducing And Hyaluronan-Binding Protein; Cell Migration Inducing Protein, Hyaluronan Binding; Cell Migration Inducing Hyaluronan Binding Protein; IR2155535; Hyaluronan Binding Protein Involved In Hyaluronan Depolymerization; Colon Cancer Secreted Protein 1; EC 3.2.1.35; CCSP1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.02M PBS, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% glycerol |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CEMIP |
|---|---|
| 全名 | Cell Migration Inducing Hyaluronidase 1 |
| 背景介绍 | Enables several functions, including clathrin heavy chain binding activity; hyaluronic acid binding activity; and hyalurononglucosaminidase activity. Involved in several processes, including hyaluronan catabolic process; positive regulation of protein phosphorylation; and positive regulation of protein targeting to membrane. Located in several cellular components, including clathrin-coated endocytic vesicle; endoplasmic reticulum; and nucleus. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.. [UniProt] |
| 细胞定位 | Cell membrane; Coated pit; Cytoplasm; Endoplasmic reticulum; Membrane. [UniProt] |
| 预测分子量 | 153 kDa |
| 翻译后修饰 | Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45839 anti-Zebrafish KIAA1199 antibody IHC-P image
Immunohistochemistry: Zebrafish liver stained with ARG45839 anti-Zebrafish KIAA1199 antibody at 2 μg/ml dilution.
