ARG65106
anti-ZYX antibody
anti-ZYX antibody for Western blot and Human
Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes ZYX |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Dog |
| 应用 | WB |
| 特异性 | Reported variants represent identical protein: NP_003452.1, NP_001010972.1 |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZYX |
| 抗原物种 | Human |
| 抗原 | C-QQREKPRVQEKQH |
| 偶联标记 | Un-conjugated |
| 別名 | Zyxin; HED-2; ESP-2; Zyxin-2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008] |
| 研究领域 | Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 61 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG65106 anti-ZYX antibody WB image
Western Blot: Peripheral Blood Mononucleocytes lysate (35 µg protein in RIPA buffer) stained with ARG65106 anti-ZYX antibody at 0.1 µg/ml dilution.
