ARG55854
anti-ZRSR2 antibody
anti-ZRSR2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ZRSR2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZRSR2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 453-482 (C-terminus) of Human ZRSR2. |
| 偶联标记 | Un-conjugated |
| 別名 | Renal carcinoma antigen NY-REN-20; RNU2; CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2; U2AF35-related protein; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2; U2; U2AF1L2; ZC3H22; URP; U2AF1RS2; U2AF1-RS2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q15696 Human U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related |
|---|---|
| 基因名称 | ZRSR2 |
| 全名 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 |
| 背景介绍 | This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008] |
| 生物功能 | Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing. [UniProt] |
| 细胞定位 | Nucleus. |
| 预测分子量 | 58 kDa |
| 翻译后修饰 | Phosphorylated in the RS domain by SRPK1. |
检测图片 (2) Click the Picture to Zoom In
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ARG55854 anti-ZRSR2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate tissue stained with ARG55854 anti-ZRSR2 antibody at 1:25 dilution.
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ARG55854 anti-ZRSR2 antibody WB image
Western blot: 35 µg of HepG2 cell lysate stained with ARG55854 anti-ZRSR2 antibody.
