ARG44995
anti-ZPR1 antibody
anti-ZPR1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes ZPR1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | ZPR1 |
| 抗原物种 | Human |
| 抗原表位 | VRYTLSVRAL EDMNREVVKT DSAATRIPEL DFEIPAFSQK GALTTVEGLI TRAISGLEQD QPARRANKDA TAERIDEFIV KLKELKQVAS PFTLIIDDPS GNSFVENPHA PQKDDALVIT HYNRTRQQEE MLGLQEEAPA EKPEEEDLRN EVLQFSTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS GGAVEPLGTR ITLHITDASD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD IRELVTKNPF TLGDSSNPGQ TERLQEFSQK MDQIIEGNMK AHFIMDDPAG NSYLQNVYAP EDDPEMKVER |
| 偶联标记 | Un-conjugated |
| 別名 | ZPR1; ZPR1 Zinc Finger; Zinc Finger Protein 259; ZNF259; Zinc Finger Protein ZPR1; GKAF |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ZPR1 |
| 全名 | ZPR1 Zinc Finger |
| 背景介绍 | The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
| 生物功能 | Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H2O2-induced neuronal cell death. [Uniprot] |
| 细胞定位 | Cell projection, Cytoplasm, Nucleus. [Uniprot] |
检测图片 (2) Click the Picture to Zoom In
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ARG44995 anti-ZPR1 antibody IHC-P image
Immunohistochemistry: Human liver stained with ARG44995 anti-ZPR1 antibody at 5 µg/mL dilution.
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ARG44995 anti-ZPR1 antibody IP image
Immunoprecipitation: K562 lysate immunoprecipitated with 2.5 µg of ARG44995 anti-ZPR1 antibody.
