ARG46698
anti-ZNF521 antibody
anti-ZNF521 antibody for Western blot,ICC/IF and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ZNF521 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZNF521 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within the last 50 amino acids of human ZNF521. |
| 偶联标记 | Un-conjugated |
| 別名 | ZNF521; EHZF; Evi3; EHZF; LIP3; Zinc finger protein 521; Early hematopoietic zinc finger protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 145 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -748°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ZNF521 |
| 全名 | zinc finger protein 521 |
| 背景介绍 | Enables protein domain specific binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron fate commitment. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 144 kDa |
| 翻译后修饰 | Phosphoprotein; Isopeptide bond; Ubl conjugation. [UniProt] |
