ARG55027
anti-ZNF281 antibody
anti-ZNF281 antibody for Western blot and Human,Mouse
Developmental Biology antibody; Gene Regulation antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ZNF281 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZNF281 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 416-450 (Center) of Human ZNF281. |
| 偶联标记 | Un-conjugated |
| 別名 | ZBP-99; GC-box-binding zinc finger protein 1; Transcription factor ZBP-99; Zinc finger protein 281; ZNP-99; Zinc finger DNA-binding protein 99 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse small intestine |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ZNF281 |
| 全名 | zinc finger protein 281 |
| 生物功能 | Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes. [UniProt] |
| 细胞定位 | Nucleus. |
| 研究领域 | Developmental Biology antibody; Gene Regulation antibody |
| 预测分子量 | 97 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG55027 anti-ZNF281 antibody WB image
Western blot: 20 µg of Mouse small intestine lysate stained with ARG55027 anti-ZNF281 antibody at 1:1000 dilution.
