ARG41190
anti-ZFYVE9 antibody
anti-ZFYVE9 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ZFYVE9 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZFYVE9 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-260 of Human ZFYVE9 (NP_004790.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Smad anchor for receptor activation; Madh-interacting protein; SMADIP; PPP1R173; SARA; hSARA; Mothers against decapentaplegic homolog-interacting protein; MADHIP; Zinc finger FYVE domain-containing protein 9; NSP; Novel serine protease; Receptor activation anchor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa | ||||
| 实际分子量 | 156 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O95405 Human Zinc finger FYVE domain-containing protein 9 |
|---|---|
| 基因名称 | ZFYVE9 |
| 全名 | zinc finger, FYVE domain containing 9 |
| 背景介绍 | This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
| 生物功能 | Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. [UniProt] |
| 细胞定位 | Cytoplasm. Early endosome membrane. [UniProt] |
| 预测分子量 | 156 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41190 anti-ZFYVE9 antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG41190 anti-ZFYVE9 antibody at 1:1000 dilution.
