ARG44990
anti-ZFP36 / Tristetraprolin antibody
anti-ZFP36 / Tristetraprolin antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes ZFP36 / Tristetraprolin |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | ZFP36 / Tristetraprolin |
| 抗原物种 | Human |
| 抗原表位 | DLAAPGHPPV LRQSISFSGL PSGRRTSPPP PGLAGPSLSS SSFSPSSSPP PPGDLPLSPS AFSAAPGTPL ARRDPTPVCC PSCRRATPIS VWGPLGGLVR TPSVQSLGSD PDEYASSGSS LGGSDSPVFE AGVFAPPQPV |
| 偶联标记 | Un-conjugated |
| 別名 | ZFP36; ZFP36 Ring Finger Protein; RNF162A; NUP475; G0S24; TTP; Tristetraprolin; TIS11; Growth Factor-Inducible Nuclear Protein NUP475; MRNA Decay Activator Protein ZFP36; G0/G1 Switch Regulatory Protein24; Zfp-36; Zinc Finger Protein36, C3H Type, Homolog (Mouse); Zinc Finger Protein36, C3H Type, Homolog; Zinc Finger Protein36 Homolog; Zinc Finger Protein36; Tristetraproline; TIS11A; GOS24 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ZFP36 |
| 全名 | ZFP36 Ring Finger Protein |
| 背景介绍 | Enables several functions, including14-3-3 protein binding activity; heat shock protein binding activity; and mRNA3'-UTR AU-rich region binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to growth factor stimulus; and regulation of gene expression. Acts upstream of or within mRNA catabolic process. Located in cytoplasmic ribonucleoprotein granule; cytosol; and nucleus. Part of ribonucleoprotein complex. Colocalizes with RISC-loading complex. [provided by Alliance of Genome Resources, Apr2022] |
| 生物功能 | Also involved in the regulation of stress granule (SG) and P-body (PB) formation and fusion. Plays a role in the regulation of keratinocyte proliferation, differentiation and apoptosis. Plays a role as a tumor suppressor by inhibiting cell proliferation in breast cancer cells. [Uniprot] |
| 细胞定位 | Cytoplasm, Exosome, Nucleus. [Uniprot] |
| 翻译后修饰 | Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44990 anti-ZFP36 / Tristetraprolin antibody IHC-P image
Immunohistochemistry: Human skin stained with ARG44990 anti-ZFP36 / Tristetraprolin antibody at 5 µg/mL dilution.
