ARG46659
anti-ZBED2 antibody
anti-ZBED2 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ZBED2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ZBED2 |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within the last 50 amino acids of human ZBED2. |
| 偶联标记 | Un-conjugated |
| 別名 | zinc finger, BED-type containing 2; ZBED2; Zinc finger BED domain-containing protein 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -709°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BTP6 Human Zinc finger BED domain-containing protein 2 |
|---|---|
| 基因名称 | ZBED2 |
| 全名 | zinc finger, BED-type containing 2 |
| 背景介绍 | Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of keratinocyte differentiation. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Transcriptional regulator which has intrinsic repressor activity and which competes with the transcriptional activator IRF1 for binding to the 5'-[CA]GAA[AC]C[CT]-3' consensus sequence in gene promoters (PubMed:32385160). May thereby play a role in keratinocyte differentiation (PubMed:31552090). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 25 kDa |
