ARG45871
anti-YTHDF1 antibody
anti-YTHDF1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Flow cytometry and Human,Mouse,Rat
概述
产品描述 | Rabbit Polyclonal antibody recognizes YTHDF1 |
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反应物种 | Hu, Ms, Rat |
应用 | FACS, ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | YTHDF1 |
抗原物种 | Human |
抗原 | Synthetic peptide corresponding to C-terminal region of human YTHDF1. |
偶联标记 | Un-conjugated |
別名 | YTHDF1; YTH N(6)-Methyladenosine RNA Binding Protein 1; DACA-1; Dermatomyositis associated with cancer putative autoantigen 1; C20orf21; YTH domain-containing family protein 1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
实际分子量 | 65 kDa |
属性
形式 | Liquid |
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纯化 | Affinity chromatography purified |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # P59326 Mouse YTH domain-containing family protein 1 Swiss-port # Q9BYJ9 Human YTH domain-containing family protein 1 |
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基因名称 | YTHDF1 |
全名 | YTH N(6)-Methyladenosine RNA Binding Protein 1 |
背景介绍 | Enables N6-methyladenosine-containing RNA reader activity and ribosome binding activity. Involved in mRNA destabilization; positive regulation of translational initiation; and stress granule assembly. Located in P-body and cytoplasmic stress granule. Implicated in colorectal cancer. [provided by Alliance of Genome Resources, Feb 2025] |
生物功能 | Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. [UniProt] |
细胞定位 | Cytoplasm. [UniProt] |
预测分子量 | 61 kDa |
翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45871 anti-YTHDF1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45871 anti-YTHDF1 antibody at 5 μg/ml dilution.
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ARG45871 anti-YTHDF1 antibody WB image
Western blot: A549 stained with ARG45871 anti-YTHDF1 antibody at 1:1000 dilution.
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ARG45871 anti-YTHDF1 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45871 anti-YTHDF1 antibody at 1 µg/10^6 cells dilution.
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ARG45871 anti-YTHDF1 antibody WB image
Western blot: Rat brain stained with ARG45871 anti-YTHDF1 antibody at 1:1000 dilution.
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ARG45871 anti-YTHDF1 antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45871 anti-YTHDF1 antibody at 1:100 dilution.
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ARG45871 anti-YTHDF1 antibody WB image
Western blot: Mouse brain stained with ARG45871 anti-YTHDF1 antibody at 1:1000 dilution.