ARG59617
anti-XPB antibody
anti-XPB antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes XPB |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | XPB |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 512-782 of Human XPB (NP_000113.1). |
| 偶联标记 | Un-conjugated |
| 別名 | TFIIH 89 kDa subunit; TFIIH basal transcription factor complex helicase XPB subunit; TTD2; RAD25; TFIIH p89; TFIIH basal transcription factor complex 89 kDa subunit; BTF2; Basic transcription factor 2 89 kDa subunit; XPB; BTF2 p89; DNA repair protein complementing XP-B cells; Xeroderma pigmentosum group B-complementing protein; EC 3.6.4.12; TFIIH; GTF2H; DNA excision repair protein ERCC-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Rat kidney, Mouse kidney and Jurkat | ||||
| 实际分子量 | 89 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ERCC3 |
| 全名 | excision repair cross-complementation group 3 |
| 背景介绍 | This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| 生物功能 | ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 89 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59617 anti-XPB antibody WB image
Western blot: 25 µg of Rat kidney, Mouse kidney and Jurkat cell lysates stained with ARG59617 anti-XPB antibody at 1:3000 dilution.
