ARG46647

anti-WSB1 antibody

anti-WSB1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes WSB1
反应物种 Hu
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 WSB1
抗原物种 Human
抗原 A 16 amino acid synthetic peptide within the last 50 amino acids of human WSB1.
偶联标记 Un-conjugated
別名 WSB1; WD repeat and SOCS box containing 1; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box-containing protein 1; WSB-1

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 46 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -697°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 26118 Human WSB1

Swiss-port # Q9Y6I7 Human WD repeat and SOCS box-containing protein 1

基因名称 WSB1
全名 WD repeat and SOCS box containing 1
背景介绍 This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能 Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation. [UniProt]
预测分子量 46 kDa
翻译后修饰 Ubl conjugation. [UniProt]