ARG45491
anti-WFS1 antibody
anti-WFS1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes WFS1 |
|---|---|
| 反应物种 | Hu, Mk |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | WFS1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human WFS1. |
| 偶联标记 | Un-conjugated |
| 別名 | WFS1; Wolframin ER Transmembrane Glycoprotein; WFS; Wolfram Syndrome 1 (Wolframin); Wolframin; DIDMOAD; CTRCT41; DFNA14; DFNA38; DFNA6; WFRS; WFSL |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 100 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | WFS1 |
| 全名 | Wolframin ER Transmembrane Glycoprotein |
| 背景介绍 | This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009] |
| 生物功能 | Participates in the regulation of cellular Ca2+ homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca2+ store. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle; Endoplasmic reticulum; Membrane. [UniProt] |
| 预测分子量 | 100 kDa |
| 翻译后修饰 | Acetylation; Glycoprotein; Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45491 anti-WFS1 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45491 anti-WFS1 antibody at 2 μg/ml dilution.
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ARG45491 anti-WFS1 antibody ICC/IF image
Immunofluorescence: HepG2 stained with ARG45491 anti-WFS1 antibody at 5 μg/ml dilution.
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ARG45491 anti-WFS1 antibody WB image
Western blot: T-47D stained with ARG45491 anti-WFS1 antibody at 0.5 μg/ml dilution.
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ARG45491 anti-WFS1 antibody FACS image
Flow Cytometry: U2OS stained with ARG45491 anti-WFS1 antibody at 1 µg/10^6 cells dilution.
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ARG45491 anti-WFS1 antibody WB image
Western blot: Monkey lung stained with ARG45491 anti-WFS1 antibody at 0.5 μg/ml dilution.
