ARG55017
anti-WDR82 antibody
anti-WDR82 antibody for ICC/IF,Western blot and Human
Gene Regulation antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes WDR82 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | WDR82 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 12-46 (N-terminus) of Human WDR82. |
| 偶联标记 | Un-conjugated |
| 別名 | PRO34047; Swd2; Protein TMEM113; WD repeat-containing protein 82; MST107; MSTP107; PRO2730; TMEM113; SWD2; WDR82A |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | SH-SY5Y |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | WDR82 |
| 全名 | WD repeat domain 82 |
| 背景介绍 | TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010] |
| 生物功能 | Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. [UniProt] |
| 细胞定位 | Nucleus Note=Associates with chromatin |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 35 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG55017 anti-WDR82 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG55017 anti-WDR82 antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
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ARG55017 anti-WDR82 antibody WB image
Western blot: 20 µg of SH-SY5Y cell lysate stained with ARG55017 anti-WDR82 antibody at 1:1000 dilution.
