概述

产品描述	Rabbit Polyclonal antibody recognizes WASF2 / WAVE2
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	WASF2 / WAVE2
抗原物种	Human
抗原	Synthetic peptide
偶联标记	Un-conjugated
別名	WASF2; WASP Family Member 2; WAVE2; SCAR2; Wiskott-Aldrich Syndrome Protein Family Member 2; Verprolin Homology Domain-Containing Protein 2; WASP Family Protein Member 2; WAS Protein Family Member 2; Actin-Binding Protein WASF2; Protein WAVE-2

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:250 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	~ 85 kDa

属性

形式	Liquid
纯化	Antigen Affinity Purified
缓冲液	PBS with 1 mg/ml BSA, 0.05% Sodium azide and 50% glycerol
抗菌剂	0.05% Sodium azide
稳定剂	1 mg/ml BSA and 50% glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10163 Human WASF2 GeneID: 242687 Mouse WASF2 Swiss-port # Q8BH43 Mouse Wiskott-Aldrich syndrome protein family member 2 Swiss-port # Q9Y6W5 Human Wiskott-Aldrich syndrome protein family member 2
基因名称	WASF2
全名	WASP Family Member 2
背景介绍	This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.
生物功能	Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
细胞定位	Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane
预测分子量	52 kDa
翻译后修饰	Phosphoprotein

检测图片 (1) Click the Picture to Zoom In