ARG11152
anti-Visinin like 1 antibody [3A9]
anti-Visinin like 1 antibody [3A9] for IHC-Frozen sections,Western blot and Human,Mouse,Rat,Cow,Pig
概述
产品描述 | Mouse Monoclonal antibody [3A9] recognizes Visinin like 1 |
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反应物种 | Hu, Ms, Rat, Cow, Pig |
应用 | IHC-Fr, WB |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 3A9 |
同位型 | IgG1 |
靶点名称 | Visinin like 1 |
抗原物种 | Human |
抗原 | Recombinant full-length Human Visinin like 1. |
偶联标记 | Un-conjugated |
別名 | HPCAL3; HUVISL1; Visinin-like protein 1; HLP3; Hippocalcin-like protein 3; VILIP; VLP-1; VILIP-1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
实际分子量 | ~ 18 kDa |
属性
形式 | Liquid |
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纯化 | Purified |
缓冲液 | PBS, 5 mM Sodium azide and 50% Glycerol. |
抗菌剂 | 5 mM Sodium azide |
稳定剂 | 50% Glycerol |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | VSNL1 |
全名 | visinin-like 1 |
背景介绍 | This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
生物功能 | Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. [UniProt] |
预测分子量 | 22 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG11152 anti-Visinin like 1 antibody [3A9] IHC-Fr image
Immunohistochemistry: Frozen section of adult rat cerebellum tissue stained with ARG11152 anti-Visinin like 1 antibody [3A9] (green) at 1:1000 dilution, and co-stained with anti-MAP2 antibody (red) at 1:10000 dilution. DAPI (blue) for nuclear staining.
Visinin like 1 antibody reveals perikarya and synaptic regions in the neuron rich granular layer (bottom) and synapse rich molecular layer (top). Note that the large prominent Purkinje neurons at the junction of these two layers do not stain with the Visinin like 1 antibody.
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ARG11152 anti-Visinin like 1 antibody [3A9] WB image
Western blot: Rat brain, Mouse brain, Pig hippocampus and Cow cerebellum lysates stained with ARG11152 anti-Visinin like 1 antibody [3A9] at 1:1000 dilution.