ARG46635

anti-VEZT antibody

anti-VEZT antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes VEZT
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 VEZT
抗原物种 Human
抗原 A 17 amino acid synthetic peptide within the last 50 amino acids of human VEZT.
偶联标记 Un-conjugated
別名 vezatin, adherens junctions transmembrane protein; VEZT; VEZATIN; Vezatin

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 60 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -685°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 215008 Mouse VEZT

GeneID: 299738 Rat VEZT

GeneID: 55591 Human VEZT

基因名称 VEZT
全名 vezatin, adherens junctions transmembrane protein
背景介绍 This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
生物功能 Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process. [UniProt]
细胞定位 Cytoplasm; Nucleus; Cell membrane; Cell projection; Cytoplasmic vesicle; Cell membrane . [UniProt]
预测分子量 63, 68, 78, 81, 83, 86 kDa