ARG45379
anti-VEGF-B antibody [6E72]
anti-VEGF-B antibody [6E72] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [6E72] recognizes VEGF-B |
|---|---|
| 反应物种 | Ms |
| 应用 | IHC-P |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 6E72 |
| 同位型 | IgG2 |
| 靶点名称 | VEGF-B |
| 抗原物种 | Mouse |
| 抗原 | Recombinant Mouse VEGF-B. |
| 偶联标记 | Un-conjugated |
| 別名 | VEGFB; Vascular Endothelial Growth Factor B; VEGFL; VRF; VEGF-Related Factor; |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P49766 Mouse Vascular endothelial growth factor B |
|---|---|
| 基因名称 | VEGF-B |
| 全名 | Vascular Endothelial Growth Factor B |
| 背景介绍 | This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] |
| 生物功能 | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45379 anti-VEGF-B antibody [6E72] IHC-P image
Immunohistochemistry: Mouse lung stained with ARG45379 anti-VEGF-B antibody [6E72].
