ARG63455
anti-VDAC2 antibody
anti-VDAC2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Pig
Metabolism antibody; Signaling Transduction antibody

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概述
产品描述 | Goat Polyclonal antibody recognizes VDAC2 |
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反应物种 | Hu, Ms, Rat, Pig |
预测物种 | Cow, Dog |
应用 | IHC-P, WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | VDAC2 |
抗原物种 | Human |
抗原 | C-GHKVGLALELEA |
偶联标记 | Un-conjugated |
別名 | Voltage-dependent anion-selective channel protein 2; hVDAC2; POR; VDAC-2; Outer mitochondrial membrane protein porin 2 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by antigen affinity chromatography. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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背景介绍 | This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
研究领域 | Metabolism antibody; Signaling Transduction antibody |
预测分子量 | 32 kDa |
翻译后修饰 | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
检测图片 (2) Click the Picture to Zoom In
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ARG63455 anti-VDAC2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human heart tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63455 anti-VDAC2 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG63455 anti-VDAC2 antibody WB image
Western blot: 35 µg of Human (A), Mouse (B) and Rat (C) brain lysates (in RIPA buffer) stained with ARG63455 anti-VDAC2 antibody at 0.3 µg/ml (A) and 1 µg/ml (B, C) dilutions and incubated at RT for 1 hour.