ARG45085
anti-VAV2 Phospho (Tyr172) antibody
anti-VAV2 Phospho (Tyr172) antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes VAV2 Phospho (Tyr172) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | VAV2 |
| 抗原物种 | Mouse |
| 抗原 | Phospho-Vav2 (Tyr-172) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-172 in mouse Vav2. This sequence has high homology with similar regions in rat and human Vav2, and has significant homology to the conserved site in Vav1 and Vav3. |
| 偶联标记 | Un-conjugated |
| 別名 | VAV2; Vav Guanine Nucleotide Exchange Factor 2; Guanine Nucleotide Exchange Factor VAV2; Vav 2 Oncogene; VAV-2; Vav 2 Guanine Nucleotide Exchange Factor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P52735 Human Guanine nucleotide exchange factor VAV2 Swiss-port # Q60992 Mouse Guanine nucleotide exchange factor VAV2 |
|---|---|
| 基因名称 | VAV2 |
| 全名 | Vav Guanine Nucleotide Exchange Factor 2 |
| 背景介绍 | VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
| 生物功能 | Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. [Uniprot] |
| 预测分子量 | 101 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
