ARG67255
anti-Uroplakin 1a antibody [SQab30373]
anti-Uroplakin 1a antibody [SQab30373] for IHC-Formalin-fixed paraffin-embedded sections and Human
. [Uniprot]
概述
| 产品描述 | Rabbit Monoclonal antibody [SQab30373] recognizes Uroplakin 1a. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30373 |
| 同位型 | IgG |
| 靶点名称 | Uroplakin 1a |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to Human Uroplakin 1a. |
| 偶联标记 | Un-conjugated |
| 別名 | UPK1A; Uroplakin 1A; TSPAN21; Tetraspanin-21; Uroplakin-1a; Uroplakin Ia; Tspan-21; UP1A; UPIA; UPKA; UP1a; UPIa; UPKa |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | UPK1A |
| 全名 | Uroplakin 1A |
| 背景介绍 | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
| 生物功能 | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. [Uniprot] |
| 细胞定位 | Membrane. [Uniprot] |
| 产品亮点 | . [Uniprot] |
| 研究领域 | . [Uniprot] |
| 预测分子量 | 29 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG67255 anti-Uroplakin 1a antibody [SQab30373] IHC-P image
Immunohistochemistry: Human Carcinoma stained with ARG67255 anti-Uroplakin 1a antibody [SQab30373] at 1:100 dilution.
