ARG59590
anti-Uroguanylin antibody
anti-Uroguanylin antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Uroguanylin |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Uroguanylin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 1-100 of Human Uroguanylin (NP_009033.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Guanylate cyclase C-activating peptide II; Guanylate cyclase activator 2B; UGN; GCAP-II |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse small intestine | ||||
| 实际分子量 | 12 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GUCA2B |
| 全名 | guanylate cyclase activator 2B (uroguanylin) |
| 背景介绍 | This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011] |
| 生物功能 | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 12 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59590 anti-Uroguanylin antibody WB image
Western blot: 25 µg of Mouse small intestine lysate stained with ARG59590 anti-Uroguanylin antibody at 1:1000 dilution.
