ARG63336

anti-USP16 / UBP-M antibody

anti-USP16 / UBP-M antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody; Gene Regulation antibody

概述

产品描述 Goat Polyclonal antibody recognizes USP16 / UBP-M
反应物种 Hu
预测物种 Ms, Rat, Cow, Dog, Pig
应用 IHC-P
特异性 This antibody is expected to recognise isoform a (NP_006438.1) and isoform b (NP_001001992.1). Reported variants represent identical protein (NP_006438.1; NP_001027582.1).
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 USP16 / UBP-M
抗原物种 Human
抗原 GKKRTKGKTVPIDD-C
偶联标记 Un-conjugated
別名 UBP-M; Deubiquitinating enzyme 16; Ubiquitin-processing protease UBP-M; Ubiquitin thioesterase 16; Ubiquitin-specific-processing protease 16; UBPM; EC 3.4.19.12; Ubiquitin carboxyl-terminal hydrolase 16

应用说明

应用建议
应用 推荐稀释比
IHC-P4 - 6 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 10600 Human USP16

Swiss-port # Q9Y5T5 Human Ubiquitin carboxyl-terminal hydrolase 16

背景介绍 This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
研究领域 Cell Biology and Cellular Response antibody; Gene Regulation antibody
预测分子量 94 kDa
翻译后修饰 Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.

检测图片 (1) Click the Picture to Zoom In

  • ARG63336 anti-USP16 / UBP-M antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Human Kidney. (Steamed antigen retrieval with Tris/EDTA buffer pH 9) stained with ARG63336 anti-USP16 / UBP-M antibody at 4 µg/ml dilution followed by HRP-staining.