ARG46631
anti-UROP11 antibody
anti-UROP11 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes UROP11 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | UROP11 |
| 抗原物种 | Mouse |
| 抗原 | A 12 amino acid synthetic peptide within the last 50 amino acids of mouse UROP11. |
| 偶联标记 | Un-conjugated |
| 別名 | Apba1; amyloid beta (A4) precursor protein binding, family A, member 1; UROP11; X11; Mint; Mint1; Lin-10; Urop11; X11alpha; 6430513E09Rik; X11; Amyloid beta A4 precursor protein-binding family A member 1; Adapter protein X11alpha; Mint-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -681°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | Apba1 |
|---|---|
| 全名 | amyloid beta (A4) precursor protein binding, family A, member 1 |
| 背景介绍 | Predicted to enable several functions, including PDZ domain binding activity; amyloid-beta binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including carboxylic acid transport; in utero embryonic development; and locomotory behavior. Located in membrane. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynaptic active zone membrane. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human APBA1 (amyloid beta precursor protein binding family A member 1). [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta (By similarity). Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (PubMed:10846156). [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus; Golgi apparatus. [UniProt] |
| 预测分子量 | 93 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
